The writer said that more miniseries will follow the recent World War II title American Vampire: Survival of the Fittest, which was illustrated by Sean Murphy (Joe the Barbarian).
"For me, that series was really supporting the concept that we'll always be doing miniseries to go along with the main book in the summers," Snyder told Comic Book Resources.
"In terms of what eras to pick, we wanted them to always be relatively concurrent with what's going on in the main series. So the next one that we're planning is going to be concurrent with the '50s stuff. It'll be called 'Lord of Nightmares' and it concerns who you'd consider to be the greatest or at least the most terrifying and powerful vampire of all time.
"The idea of the miniseries is that they'll always be from the human perception or the [vampire hunting] Vassals' perception of the vampires. They'll be the place to go so you can learn a lot more about the mythology as it's understood by humans as well as the history of vampires.
"All the secrets you've been wondering about and the history when it comes to vampires that exist in our world of American Vampire will happen there."
Snyder is currently writing DC Comics' Batman and Swamp Thing.
The core series will enter a new arc called 'Death Race' in American Vampire #22. Set in the 1950s, it will debut on December 28.