Microsoft's Major Nelson revealed that the company would team up with Activision to live stream gameplay footage on August 15 at 5pm BST (9am PT, 12pm ET).
In addition to the world's first multiplayer gameplay footage, the live stream will feature interviews with members of the development team Treyarch.
It will be broadcast on Xbox Live, Facebook, Xbox.com and the Call of Duty website. Repeats will also be shown on Xbox Live and Call of Duty.com.
Activision recently debuted the first Black Ops 2 multiplayer trailer.
The video showcases the game's futuristic firearms and projectiles, as well as new perks including controllable drones and a device that blinds foes with solar reflections.
A number of multiplayer changes were rumoured before the game's official announcement earlier this year.
Black Ops 2 is set during a 21st-century Cold War and will release on November 13 on Xbox 360, PS3 and PC.
GAME has announced a number of pre-order perks from its stores, while all consumers that reserve the game will receive the Nuketown 2025 multiplayer map.
> Read our preview of Black Ops 2
Watch the Black Ops 2 multiplayer trailer below: