Beyoncé, Colin Farrell, Amanda Seyfried, Johnny Knoxville and Josh Hutcherson are among the voice cast of the upcoming animated project.
The film is produced by Blue Sky Studios, the team behind the Ice Age movies.
Epic follows a teenage girl who is transported to a secret world, and has to team up with a group of characters to save both the real and fantasy worlds.
A group of doodlebugs attempt to reach the 'Leaf Men' in order to save an old woman's garden that they live in, but must face the dangers of the Spider Queen and her goblins.
The film will be released on May 24, 2013.