The director formally bid farewell to Batman in a foreword to new book The Art and Making of The Dark Knight Trilogy, saying that he will "miss" the Caped Crusader.
Nolan has now told Empire that it makes sense for the franchise to be rebooted at some point.
"When I first met with Paul Levitz of DC Comics prior to Batman Begins, he explained to me clearly that Batman, of all superheroes, has thrived on reinterpretation and almost is strengthened by it," the filmmaker explained. "I'm talking about over the years in the comic books but also in the movies."
He continued: "So when the time is right, whenever someone does whatever the next iteration of the character is, they simply need to be true.
"[Be true] to whatever it is they want to see, to what they believe in, not worry too much about what everyone else is telling them it should be."
Christian Bale - who played Batman in Nolan's trilogy - recently said that he would be "very intrigued" to see the franchise rebooted at some point.
"It would be very interesting to see what someone else does with the character. I'd be the first one there to watch," he declared.
On Tuesday (July 24), Bale flew to Aurora, CO to visit the victims of a shooting that took place at a Dark Knight Rises screening.
Watch a trailer for The Dark Knight Rises below: