The Rock of Ages star revealed that he is content with the three kids he already has - Connor and Bella, with his ex-wife Nicole Kidman, and Suri, with his wife Katie Holmes.
"I'm so happy with three," Cruise told People.
"I'm enjoying every second with Suri that I have," he continued. "And I'm enjoying the relationship with my older kids, and the way it is right now."
Earlier this week, the 49-year-old revealed that his 6-year-old daughter was taken aback by his make-up for Rock of Ages.
Cruise recently began shooting the sci-fi film Oblivion in New York City.
Rock of Ages opens in UK cinemas on June 13 and in the US on June 15.
Watch the trailer for Rock of Ages below: