Soap fans can cast their votes across 14 categories, celebrating the highlights and best performances from the past 12 months.
As with previous years, the longlist sees nominees from Coronation Street, EastEnders, Emmerdale and Hollyoaks represented equally across most of the categories, which include 'Best Actor', 'Best Actress', 'Best Newcomer' and 'Best Young Actor'.
The 12 stars in the running for this year's 'Best Actor' prize include Coronation Street's Chris Gascoyne, EastEnders' Steve McFadden, Emmerdale's Steve Halliwell and Hollyoaks' Emmett Scanlan.
Meanwhile, Alison King (Coronation Street), Jessie Wallace (EastEnders), Lucy Pargeter (Emmerdale) and Karen Hassan (Hollyoaks) are among the 12 'Best Actress' nominees.
Weatherfield's Natalie Gumede, Walford's Hetti Bywater, Emmerdale star Gemma Oaten and Hollyoaks actor Steven Roberts are among those with 'Best Newcomer' nods, while the 'Best Young Actor' category includes Alex Bain (Coronation Street), Maisie Smith (EastEnders), Eden Taylor-Draper (Emmerdale) and Ellis Hollins (Hollyoaks).
Other categories featuring nominees from the big four soaps are 'Funniest Male', 'Funniest Female', 'Best Bad Boy', 'Best Bitch', 'Sexiest Male' and 'Sexiest Female'. Additionally, the shows will battle it out for the highly-coveted 'Best Soap' title.
Doctors, Neighbours and Home and Away are also represented in the awards as there are 'Best Daytime Star' and 'Best Daytime Soap' categories.
Finally, Casualty, Holby City and Waterloo Road are in the running for 'Best Drama'.
Last year's Inside Soap Awards saw EastEnders win big on the night, taking home five prizes including 'Best Soap'.
Votes can be cast via a form in the latest issue of Inside Soap, which is out on July 10. Fans can also vote by visiting the Inside Soap website.
> Read the full list of longlist nominees for the Inside Soap Awards 2012
Photo gallery - Inside Soap Awards 2012 nominees: