The former Footballers' Wives and EastEnders actress has signed up for the role of Carol Barry, the head of a Liverpudlian criminal family who have been tipped to cause mayhem in upcoming storylines.
Pictured: Zöe Lucker and Alec Newman.
As Carol's husband is in prison, she is the lone parent of three unruly children - bad boy Barry (Carl Au) and daughters Dynasty and Kacey (Abby Mavers and Brogan Ellis).
Viewers will see the kids arrive at Waterloo Road's new home in Scotland as the latest recruits for headmaster Michael Byrne's pupil referral unit. Michael (Alec Newman) hopes to turn them into model students, but it quickly becomes apparent that top grades are the last thing on their minds.
Lucker commented: "I'm delighted to join the cast of Waterloo Road and work with Shed and the BBC again. It's a show I've always enjoyed and I'm thrilled to be part of the outrageous Barry family.
"Carol and her kids are going to ruffle plenty of feathers in Waterloo Road - you can't trust them as far as you can throw them! They're a family of great characters - you just wouldn't want the Barrys in your neighbourhood!"
Waterloo Road is Lucker's first major project since bowing out as Vanessa Gold in EastEnders last year.
Pictured: Lucker as Vanessa in EastEnders.
Cameron Roach, head of drama for Shed Productions and executive producer of Waterloo Road, said: "Zöe is a terrific addition to our ensemble cast. It is incredibly exciting to be working with her again after working together on Footballers' Wives. This time her character's not about the glamour but keeping the family together."
BBC Scotland's executive producer Gaynor Holmes added: "We'd like to extend a warm welcome to Zöe as she arrives in Scotland. It's very exciting to see Waterloo Road continue to attract such star casting as the show goes from strength to strength."
Waterloo Road fans will see the Barry family make their on-screen debut next year, in episodes currently being filmed at the programme's new base in Greenock, Scotland.