In an hour-long live episode which aired this evening, the new mum - played by Vicky Binns - tragically passed away before a rescue team could free her from the rubble in the wrecked Corner Shop.
Shortly before Molly's death, close friend Sally Webster (Sally Dynevor) came to her side in order to provide moral support in her time of need. However, as Molly realised that she only had moments left to live, she dramatically came clean over her affair with Sally's husband Kevin.
Making future plans for the baby she had with Kevin, a dying Molly told Sally: "I didn't want to hurt you. Jack's not going to have his mummy - he's going to need his daddy… It's Kevin, I'm sorry."
Molly passed away shortly after her confession, leaving Sally to break the news of her death to the shop worker's partner Tyrone.
Tonight's live episode also saw a critical Peter Barlow marry Leanne Battersby in hospital as he believed he was about to die. However, as soon as he said his vows, he dramatically flatlined - leaving his future uncertain.
Meanwhile, the death of Ashley Peacock was also confirmed on screen and Fiz Stape was seen giving birth to a baby girl, who she named Hope.
Later, the nightmare faced by Fiz's husband John continued as he tried to disguise Charlotte Hoyle's lifeless body as part of the tram crash carnage - only to be told by a paramedic that she still had a weak pulse.
As Coronation Street's birthday celebrations continue tomorrow night, fans are expected to discover whether Peter will become the third casualty of the week, whether Rita Sullivan will be found in the wrecked Kabin and how John will get out of his latest fix.
> Click here to read more about Corrie's 50th anniversary