It was announced in May that the actress, who plays Sian Powers, would be leaving the ITV1 soap in early 2012.
She filmed her final scenes for Coronation Street last week and was met by fans outside Granada Studios in Manchester, where a surprise party was held.
Parkinson was joined by her on-screen girlfriend Brooke Vincent, who plays Sophie Webster, The Sun reports..
She was said to be overwhelmed as fans gave her gold balloons that spelled her name alongside a cake and other gifts.
Speaking of her exit, Parkinson recently admitted that she has mixed feelings about leaving Coronation Street.
"I'm very sad but I'm very excited," she said. "I'm in two minds, I don't know whether I'll regret my decision or not but as it's come closer I know it's what I need to do.
"But it's a sad place to leave because everyone's like a family and everyone's so close. But I only live round the corner so I'll be popping in every day."
> Coronation Street films dramatic Sophie, Sian wedding scenes